Omega-3 and silent inflammation.

The Omega-3 index is one of the best-validated markers for cardiovascular risk. What it really tells you.

January 2026

We explain how the Omega-3 index is formed, what a shift means, and which supplementation is appropriate.

Dietary omega-6 linoleic acid (LA) is converted in the body into omega-6 arachidonic acid (AA) and stored in our cell membranes. From arachidonic acid arise bioactive compounds that can trigger acute inflammation and also fuel chronic inflammation, with potential downstream effects on various health issues.

Compared to the diet the human body is evolutionarily adapted to, today's diet in Western societies generally lacks omega-3 fatty acids, which act as anti-inflammatories.

All cells produce free radicals and reactive oxygen species that can attack the polyunsaturated fatty acids, such as omega-3 and omega-6, in cell membranes. To prevent this, the body maintains its own defence mechanism. Oxidative stress occurs when an imbalance arises between the production of these breakdown products (free radicals) and the body's own defence lines (antioxidants).

In short: for cellular health, unsaturated fatty acids, both omega-6 and omega-3, are essential in a balanced amount. To avoid inflammatory processes in the body and keep cell membrane function undisturbed, the balance between omega-6 and omega-3 needs to be maintained.

More pieces to follow. Topic suggestions welcome.